Medical Library
140 evidence-based articles + 10 holistic-medicine book reviews — in each of the 3 languages. Endocrinology, metabolism, nutraceuticals, anti-aging. Scientific perspective without populism.
Diabetes & Remission
6
A New Word in Type 2 Diabetes Treatment and NAD+ Activation: Imeglimin
In June 2021, Japan approved a type 2 diabetes tablet unlike any existing class: imeglimin acts on the mitochondrion — t…
500+ Patients in Remission: What Standard Medicine Gets Wrong About Type 2 Diabetes
She was 54, had lived with diabetes for 11 years, and was on four medications. They told her the disease was progressive…
Can Type 2 Diabetes Be Cured? A Scientific Look at Remission
"Can type 2 diabetes be cured?" — millions of people ask this question worldwide. Conventional medicine says no, only ma…
Endocrinology
11Orforglipron: the first pill instead of an injection — and what it actually does
Every GLP-1 drug so far has been an injection — not by design but by chemistry: they are proteins, and the stomach diges…
The Autoimmune Protocol (AIP) in Hashimoto's Thyroiditis: What Two Studies Actually Showed
The autoimmune protocol promises what patients want most: stopping the disease with food. Evidence exists — exactly two …
Gluten-free diet in Hashimoto's thyroiditis: who it helps and who it does not
Dropping gluten has become folk therapy for Hashimoto's — attempted alone, without testing and without an indication. Th…
Metabolism & Weight
4
MOTS-c: a peptide from the mitochondrion’s own DNA that responds to exertion
The mitochondrion is remembered as the plant that makes energy. It turns out to have a voice as well: inside its own DNA…
Sepiapterin (Sephience) in Phenylketonuria: A Drug Measured by the Plate
In phenylketonuria the enzyme cannot keep up with phenylalanine, which builds up in the blood and poisons the developing…
Obesogens: Why Diet and Exercise Are Not Enough. Book Review: Blumberg "The Obesogen Effect"
The obesity pandemic cannot be explained by "eat less, move more" alone. Professor Bruce Blumberg of UC Irvine coined th…
Thyroid
21
Iron and thyroid pills: why 4 hours, and when to check ferritin
One person can take a thyroid pill and iron if the two are separated in time — though even the gap does not help everyon…
Which Mental Illness Is Linked to Hypothyroidism? Depression, Anxiety, and Hashimoto's
A patient has been on antidepressants for five years with no lasting effect — nobody ever checked TPO antibodies. A case…
TSH Is a Pituitary Hormone, Not a Thyroid Hormone: The Single-Test Blind Spot
When a clinician orders "just TSH" — they measure pituitary function, not thyroid function. TSH is a late, inertial mark…
Supplements & Nutraceuticals
6Amla (10:1 Extract): What the Research Shows, and What Turned Out to Be a Legend
Two kinds of things get written about amla: enthusiastic legends, and nothing. The legends are easy to check — the famou…
Black Cumin (Nigella sativa): 82 Trials, Five Systems of Recovery
Black cumin is an ancient spice with 82 RCTs and a GRADE-A meta-analysis on cardiometabolic endpoints today. The active …
Cordyceps: Why Wild Himalayan and Lab-Grown Are Two Different Products
Cordyceps supplements have surged in popularity, but wild Himalayan cordyceps and lab-grown varieties are fundamentally …
Anti-Aging
3
Ten healthy diets compared against biological age. The gap between them is smaller than it looks
German researchers took ten recognised healthy-eating scores — Mediterranean, DASH, MIND, Nordic and others — and matche…
Spontaneous Remissions: Anomaly or Unstudied Mechanism? Alexander (Cureus, 2025) and RRMI
Medicine calls it an anomaly. But the data says otherwise. 60 documented cases of radical remission — unexpected recover…
NAD+ and Cellular Aging: What's Behind the Hype
NAD+ (nicotinamide adenine dinucleotide) is a central coenzyme of energy metabolism whose levels decline by roughly 50% …
Diagnostics
5
Haemochromatosis is not missed in the lab report — most often, the test is simply never ordered
Hereditary haemochromatosis is found late not because it is hard to recognise, but because the right test is most often …
Transferrin saturation: why a single number cannot be trusted
A single high transferrin saturation is not a diagnosis, and not even grounds for genetic testing. In five short pages: …
Ferritin and Hair Loss: How Much Iron Is Actually Needed
"Check your ferritin" is the most common advice given for hair loss, and it is also the most commonly misread result. Fe…
Neurology
23The Strongest Opioid Painkillers: What Potency Actually Means
A list of opioids by potency reads like a ranking: sufentanil, fentanyl, buprenorphine, then the rest. But the study tho…
Suzetrigine (Journavx): The First Non-Opioid Painkiller of a New Class in Decades
For the first time in decades a painkiller has arrived with a genuinely new mechanism: it switches off a sodium channel …
Etoricoxib (Arcoxia): The Strongest Non-Opioid — and What That Actually Means
Etoricoxib holds the best figure among non-opioid painkillers: fewer than two people need treating for one of them to ge…
Cardiology
27
Elamipretide (Forzinity) in Barth Syndrome: A Drug Approved Despite a Failed Trial
Barth syndrome is a disease of twelve boys in a clinical trial and a few hundred people worldwide. Elamipretide braces t…
Inclisiran (Leqvio): The Twice-a-Year Cholesterol Injection — What Is Proven and What Is Not
Two injections a year instead of a daily tablet sounds like marketing, but behind it lies a genuinely different level of…
Mavacamten (Camzyos): A Short Guide to the Drug That Relaxes an Overpowered Heart
In hypertrophic cardiomyopathy the heart is not weak — it is too strong: the muscle is thickened, contracts excessively …
Gastroenterology
16
Berberine for SIBO: first in the ranking, with nothing yet to compare it against
Berberine came first in a network meta-analysis of SIBO treatments — and that is true. But a ranking is not «it beat rif…
SIBO: what the breath test shows, and why the order of steps matters more than the remedy
SIBO is both under-recognised and over-diagnosed, and the same breath test is responsible for each. What it actually mea…
Givosiran (Givlaari) in Acute Hepatic Porphyria: Switching Off Attacks That Should Not Happen
An acute porphyria attack means days of unbearable abdominal pain with no surgical cause, joined by vomiting, swings in …
Book Reviews
10
Outlive — Peter Attia: three ideas that reshape the approach to longevity
Peter Attia, a physician and longevity researcher, reframes what "treating" means in his book "Outlive" (2023). Three ke…
The Hormone Cure — Sara Gottfried: cortisol, thyroid, and estrogen dominance
Sara Gottfried, a Harvard-trained gynaecologist, formulates three theses in "The Hormone Cure" (2013) that have reshaped…
Why We Sleep — Matthew Walker: four phases, sleep debt and brain clearance
Matthew Walker, a neuroscientist at UC Berkeley, formulates three ideas in "Why We Sleep" (2017): the four phases of sle…