Medical Library
134 evidence-based articles + 10 holistic-medicine book reviews — in each of the 3 languages. Endocrinology, metabolism, nutraceuticals, anti-aging. Scientific perspective without populism.
Diabetes & Remission
6
A New Word in Type 2 Diabetes Treatment and NAD+ Activation: Imeglimin
In June 2021, Japan approved a type 2 diabetes tablet unlike any existing class: imeglimin acts on the mitochondrion — t…
500+ Patients in Remission: What Standard Medicine Gets Wrong About Type 2 Diabetes
She was 54, had lived with diabetes for 11 years, and was on four medications. They told her the disease was progressive…
Can Type 2 Diabetes Be Cured? A Scientific Look at Remission
"Can type 2 diabetes be cured?" — millions of people ask this question worldwide. Conventional medicine says no, only ma…
Endocrinology
11Orforglipron: the first pill instead of an injection — and what it actually does
Every GLP-1 drug so far has been an injection — not by design but by chemistry: they are proteins, and the stomach diges…
The Autoimmune Protocol (AIP) in Hashimoto's Thyroiditis: What Two Studies Actually Showed
The autoimmune protocol promises what patients want most: stopping the disease with food. Evidence exists — exactly two …
Gluten-free diet in Hashimoto's thyroiditis: who it helps and who it does not
Dropping gluten has become folk therapy for Hashimoto's — attempted alone, without testing and without an indication. Th…
Metabolism & Weight
4
MOTS-c: a peptide from the mitochondrion’s own DNA that responds to exertion
The mitochondrion is remembered as the plant that makes energy. It turns out to have a voice as well: inside its own DNA…
Sepiapterin (Sephience) in Phenylketonuria: A Drug Measured by the Plate
In phenylketonuria the enzyme cannot keep up with phenylalanine, which builds up in the blood and poisons the developing…
Obesogens: Why Diet and Exercise Are Not Enough. Book Review: Blumberg "The Obesogen Effect"
The obesity pandemic cannot be explained by "eat less, move more" alone. Professor Bruce Blumberg of UC Irvine coined th…
Thyroid
20
Which Mental Illness Is Linked to Hypothyroidism? Depression, Anxiety, and Hashimoto's
A patient has been on antidepressants for five years with no lasting effect — nobody ever checked TPO antibodies. A case…
TSH Is a Pituitary Hormone, Not a Thyroid Hormone: The Single-Test Blind Spot
When a clinician orders "just TSH" — they measure pituitary function, not thyroid function. TSH is a late, inertial mark…
T3 — the Only Active Thyroid Hormone: Why It Works Inside the Cell
T3 is the only thyroid hormone that actually works. And it works not in blood but inside the cell, at the nuclear recept…
Supplements & Nutraceuticals
6Amla (10:1 Extract): What the Research Shows, and What Turned Out to Be a Legend
Two kinds of things get written about amla: enthusiastic legends, and nothing. The legends are easy to check — the famou…
Black Cumin (Nigella sativa): 82 Trials, Five Systems of Recovery
Black cumin is an ancient spice with 82 RCTs and a GRADE-A meta-analysis on cardiometabolic endpoints today. The active …
Cordyceps: Why Wild Himalayan and Lab-Grown Are Two Different Products
Cordyceps supplements have surged in popularity, but wild Himalayan cordyceps and lab-grown varieties are fundamentally …
Anti-Aging
2
Spontaneous Remissions: Anomaly or Unstudied Mechanism? Alexander (Cureus, 2025) and RRMI
Medicine calls it an anomaly. But the data says otherwise. 60 documented cases of radical remission — unexpected recover…
NAD+ and Cellular Aging: What's Behind the Hype
NAD+ (nicotinamide adenine dinucleotide) is a central coenzyme of energy metabolism whose levels decline by roughly 50% …
Diagnostics
3
Ferritin and Hair Loss: How Much Iron Is Actually Needed
"Check your ferritin" is the most common advice given for hair loss, and it is also the most commonly misread result. Fe…
CGM Sensors: How Real-Time Glucose Monitoring Is Changing Diabetes Treatment
Continuous glucose monitoring (CGM) has revolutionized diabetes management by providing real-time data instead of isolat…
HOMA-IR: The Blood Test Your Doctor Isn't Ordering (But Should Be)
Your doctor measures fasting glucose and HbA1c but never orders fasting insulin or calculates HOMA-IR. That's like check…
Neurology
23The Strongest Opioid Painkillers: What Potency Actually Means
A list of opioids by potency reads like a ranking: sufentanil, fentanyl, buprenorphine, then the rest. But the study tho…
Suzetrigine (Journavx): The First Non-Opioid Painkiller of a New Class in Decades
For the first time in decades a painkiller has arrived with a genuinely new mechanism: it switches off a sodium channel …
Etoricoxib (Arcoxia): The Strongest Non-Opioid — and What That Actually Means
Etoricoxib holds the best figure among non-opioid painkillers: fewer than two people need treating for one of them to ge…
Cardiology
27
Elamipretide (Forzinity) in Barth Syndrome: A Drug Approved Despite a Failed Trial
Barth syndrome is a disease of twelve boys in a clinical trial and a few hundred people worldwide. Elamipretide braces t…
Inclisiran (Leqvio): The Twice-a-Year Cholesterol Injection — What Is Proven and What Is Not
Two injections a year instead of a daily tablet sounds like marketing, but behind it lies a genuinely different level of…
Mavacamten (Camzyos): A Short Guide to the Drug That Relaxes an Overpowered Heart
In hypertrophic cardiomyopathy the heart is not weak — it is too strong: the muscle is thickened, contracts excessively …
Gastroenterology
14
Givosiran (Givlaari) in Acute Hepatic Porphyria: Switching Off Attacks That Should Not Happen
An acute porphyria attack means days of unbearable abdominal pain with no surgical cause, joined by vomiting, swings in …
Resmetirom (Rezdiffra): The First Drug for Fatty Liver Disease — A Short Guide
Fatty liver disease affects roughly one adult in three, and until 2024 there was no treatment for it — only "lose weight…
Vonoprazan (Voquezna): An Acid Blocker That Does Not Work Like Omeprazole — A Short Guide
Omeprazole and its relatives are imperfect for three reasons: they must be taken before food, they take days to reach fu…
Book Reviews
10
Outlive — Peter Attia: three ideas that reshape the approach to longevity
Peter Attia, a physician and longevity researcher, reframes what "treating" means in his book "Outlive" (2023). Three ke…
The Hormone Cure — Sara Gottfried: cortisol, thyroid, and estrogen dominance
Sara Gottfried, a Harvard-trained gynaecologist, formulates three theses in "The Hormone Cure" (2013) that have reshaped…
Why We Sleep — Matthew Walker: four phases, sleep debt and brain clearance
Matthew Walker, a neuroscientist at UC Berkeley, formulates three ideas in "Why We Sleep" (2017): the four phases of sle…