
Essential Support Cream for Women
Description
Transdermal cream with bioidentical hormones for women after 40. 50 ml bottle with a metered pump. Dermatologically tested for sensitive skin. Manufactured by Sarati International, Inc., Los Fresnos, TX, USA.
💊 Each full press of the pump provides:
▪︎ Progesterone — 20 mg
▪︎ Aloe Barbadensis Leaf Juice — 20 mg
▪︎ Tocopheryl Acetate (vitamin E) — 10 mg
▪︎ Grapefruit Seed Extract — 5 mg
▪︎ Estradiol — 5 mg
▪︎ Estriol — 5 mg
▪︎ Plant-based phyto-estrogen blend — 5 mg (Soya, Dong Quai, Black Cohosh, Red Clover Blossom, Licorice Root, Wild Yam)
🔬 Why the transdermal route:
▪︎ An oral tablet passes through the liver first, where the synthesis of clotting factors increases — hence the higher thrombotic risk of oral estrogens
▪︎ Applied to the skin, the hormone enters the bloodstream directly, bypassing first-pass hepatic metabolism
▪︎ This is why the transdermal form is preferred when vascular risk factors are present
🌿 Why progesterone and estriol are included:
▪︎ Estrogen without progesterone thickens the endometrium; progesterone restrains that thickening — with an intact uterus they are prescribed together, as a rule rather than a preference
▪︎ Estriol is the mildest of the three estrogens, with a marked tropism for the urogenital area — dryness and discomfort
✅ Free from: parabens, sulfates, silicones, artificial fragrance.
🕒 Use: apply to clean skin as directed by your physician. The dose and duration are selected by a doctor based on lab results and your history.
⚠️ Contraindications: history of breast or endometrial cancer, previous thrombosis, severe liver disease, undiagnosed uterine bleeding. In these situations the topical form is contraindicated just as tablets are. This is hormone therapy in a convenient form, not a cosmetic product.



