
Acarphage (Acarbose) 50 mg tablets
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Description
Alpha-glucosidase inhibitor for type 2 diabetes and prediabetes (impaired glucose tolerance). Italian generic of Glucobay (Bayer) by Bruno Farmaceutici, «medicinale equivalente»; 40 tablets of 50 mg.
💊 Composition:
▪︎ Acarbose — 50 mg per tablet
🔬 Mechanism:
▪︎ Blocks the brush-border enzymes of the small intestine that cut starch and sucrose into glucose, so post-meal glucose rises more slowly and lower
▪︎ Acts in the gut lumen: less than 2 % of the dose is absorbed
▪︎ Does not cause hypoglycemia on its own
🧬 Evidence:
▪︎ STOP-NIDDM (1,429 people with prediabetes, 3.3 years): 25 % lower risk of progression to type 2 diabetes
▪︎ ACE (6,522 patients, 5 years): 18 % fewer new cases of diabetes
▪︎ MARCH (788 newly diagnosed patients, 48 weeks): HbA1c lowering equal to metformin
▪︎ Meta-analyses: about 1.2 kg less body weight than placebo and than DPP-4 inhibitors
🕒 Dosing: with the first mouthful of a meal, starting at 50 mg and increasing gradually, up to 50–100 mg three times a day, exactly as prescribed by your physician
⚠️ Prescription drug (Rx): requires physician assessment, prescription and lab monitoring. Most common side effects are bloating, gas and diarrhea, usually fading with slow dose escalation. Contraindicated in inflammatory bowel disease, intestinal obstruction, malabsorption, severe renal impairment, cirrhosis, pregnancy and breastfeeding. Hypoglycemia with insulin or sulfonylureas is treated with pure glucose only.
📦 Original Italian product. Ordered on request via chat — availability and current price are confirmed by the administrator.
Research & citations
- Большой разбор акарбозы в блоге Universum
- STOP-NIDDM: acarbose for prevention of type 2 diabetes (Lancet 2002)PMID 12086760
- MARCH: acarbose vs metformin as initial therapy (Lancet Diabetes Endocrinol 2014)PMID 24622668
- Network meta-analysis: acarbose vs DPP-4 inhibitors, weight loss (2020)PMID 32582019



