SAMYR*IM EV 5FL 400mg+5fiale 5ml

S-Adenosyl-L-Methionine (Ademetionine Injections)

▪ Dosage form: 5 vials of lyophilized powder 400 mg + 5 vials of solvent 5 ml
▪ Manufacturer: Italy
▪ Route of administration: intravenous drip or intramuscular injection

🧪 Composition:
▪ One vial of powder contains:
– 400 mg ademetionine
– 1,4-butandisulfonate (760 mg) — stabilizing form

▪ One vial of solvent contains:
– Water for injections
– L-lysine
– Sodium hydroxide

🔬 Mechanism of action of Samyr:
▪ Ademetionine participates in methylation reactions — critical for detoxification, hormone and enzyme synthesis
▪ Is a precursor of thiol compounds — cysteine, taurine, glutathione, coenzyme A
▪ Supports liver cell regeneration and membrane stabilization
▪ Enhances antioxidant protection of the liver (by increasing glutathione levels)
▪ Stimulates collagen and glycosaminoglycan synthesis — substances necessary for joints
▪ Increases synthesis of neurotransmitters: serotonin, dopamine, adrenaline
▪ Exhibits an antidepressant effect appearing from the end of the 1st week of therapy

✅ Indications:
▪ Chronic diffuse liver diseases:
– cirrhosis
– hepatitis (viral, toxic)
– intrahepatic cholestasis
▪ Cholestatic syndrome (including itching)
▪ Asthenoneurotic and depressive states, including hypochondriac
▪ Psychosomatic disorders against the background of chronic intoxication
▪ Complex therapy of joint and ligament diseases

🧠 Psychotropic effect:
▪ Samyr acts as an antidepressant:
– Increases serotonin and dopamine levels
– Improves mood, reduces anxiety
– Eliminates chronic fatigue syndrome
– Without side effects typical for traditional antidepressants
– Effect occurs within 3–7 days, while SSRIs take 3–4 weeks

🧬 Why additional intake is important:
🔸 Although S-adenosyl-L-methionine is synthesized by the body, in cases of:
– liver diseases
– chronic stress
– methionine deficiency
– aging
its production sharply decreases.

📌 In such cases, additional administration via injections or drips is necessary to ensure normal liver, brain, and joint function.

📋 Consult your doctor before use.